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Cushing’s Disease in Dogs: Symptoms, Diagnosis, and Care Tips

by Craig Fields 31 Mar 2025
Cushing’s Disease in Dogs: Symptoms, Diagnosis, and Care Tips

Each year, thousands of dogs are diagnosed with Cushing's disease, a condition that primarily affects older pups. If your dog has been diagnosed—or if you suspect something might be off—it can feel overwhelming to figure out what's next. Understanding Cushing's syndrome and exploring treatment options is key to helping your furry friend stay happy and healthy. While traditional treatments exist, many pet owners are looking for natural alternatives to support their dog's well-being.

In this guide, we'll break down Canine Cushing's disease, common symptoms to watch for, and how CBD and medicinal Mushrooms may offer relief. Let's explore the options to keep your pup feeling their best!

Understanding Cushing's Disease in Dogs

Canine Cushing's Disease is a hormonal disorder that occurs when a dog's body produces too much cortisol. This hormone plays a crucial role in managing stress, weight, immune function, and blood sugar levels. However, excessive cortisol can lead to serious health issues, affecting your dog's overall well-being.

Cushing's Syndrome and Disease typically affects middle-aged and older dogs and comes in three forms:

  • Pituitary-Dependent Cushing's – The most common type, affecting 80-90% of cases, is caused by a tumor on the pituitary gland.

  • Adrenal-Dependent Cushing's – Occurs in about 15% of cases and is caused by a tumor on the adrenal glands.

  • Iatrogenic Cushing's – The least common form, caused by long-term steroid use.

Recognizing the type of Canine Cushing's your dog has is the first step in finding the right treatment plan to help them live a healthier, happier life.

The symptoms of Cushing's syndrome

Cushing's disease in dogs can be tricky to spot because many of its symptoms look like typical signs of aging. If you notice changes in your dog's behavior or appearance, paying attention is important. Common signs and cushing's disease symptoms include increased thirst and hunger, frequent urination (including accidents indoors), and excessive panting. Some dogs may develop thinning skin, hair loss, or a potbelly. They might also seem more tired or less active than usual. Also, recurring skin infections or unusual skin growths can be red flags. If you notice any of these symptoms, visiting the vet can help determine the best course of action for your pup's health.

How Common is Canine Cushing's Disease ?

Cushing's disease is relatively common in dogs, especially as they get older. Some breeds, like Beagles, Boston Terriers, Boxers, Dachshunds, German Shepherds, Golden Retrievers, Labrador Retrievers, Poodles, and Terriers, are more prone to developing the condition.

Diagnosing Cushing's in dogs can be tricky, and some dogs may even be misdiagnosed. If you suspect your dog has Cushing's, a veterinarian can run tests like a blood test, ACTH Stimulation Test, or Cortisol-Creatinine Ratio Test to check cortisol levels. An ultrasound is often used alongside these tests to confirm the diagnosis.

CBD for Dogs with Cushing's Disease: A Natural Alternative

Traditional treatments for Cushing's disease in dogs often include hormone-regulating medications like trilostane or mitotane. Surgery may be an option in some cases, but it can be risky—especially for older dogs.

CBD oil offers a natural alternative for pet owners looking for a gentler approach. Research and real-life cases suggest that full-spectrum CBD oil may help manage hormonal imbalances and could even shrink or eliminate the tumors responsible for Cushing's disease. By choosing CBD, you can support your dog's health without the stress of invasive procedures or potential side effects from medications.

How CBD Can Help Dogs with Cushing's Disease

CBD offers several potential benefits for dogs and cushing disease by addressing the root causes and symptoms of the condition.

  • Helping to Slow Tumor Growth – Cushing's disease is often caused by tumors on the adrenal or pituitary glands. CBD has been shown to support natural cell death (apoptosis) in abnormal cells and may help slow tumor growth by preventing the formation of blood vessels that feed tumors.

  • Balancing Hormones – The body's endocannabinoid system plays a key role in regulating hormones, including cortisol, which is often overproduced in dogs with Cushing's. CBD helps restore balance, supporting overall health and well-being.

  • Easing Symptoms – By promoting balance within the body, CBD may help relieve symptoms like excessive thirst, frequent urination, and skin issues, improving your dog's overall quality of life.

Medicinal Mushrooms For Canine Cushing's Disease

Certain medicinal mushrooms, like Reishi, Shiitake, Turkey Tail, Cordyceps, and Lion's Mane, are known for their powerful immune-boosting and antioxidant properties. These natural benefits may help support dogs with cushing syndrome in dogs by promoting overall wellness. Shiitake mushrooms, in particular, have been linked to potential benefits for managing Cushing's symptoms. These mushrooms contain compounds like beta-glucans and polysaccharides, which are believed to support immune function and overall health. Adding medicinal mushrooms to your dog's diet could be a natural way to help them feel their best.

Our 5-in-1 Blend Mushroom Tincture is a natural way to support your dog's overall health and well-being. Made with powerful medicinal mushrooms—Turkey Tail, Lion's Mane, Cordyceps, Shiitake, and Reishi—it helps balance hormones, reduce inflammation, boost energy levels, and strengthen the immune system. Whether your dog is dealing with age-related issues or chronic conditions or needs an extra wellness boost, this gentle, holistic remedy provides essential support without the risk of harsh side effects. Incorporating this blend into your pet's routine gives them a natural and effective way to feel their best every day.

A Healthier Path: How Mushrooms Helped My Dog Mac Overcome Cushing's Disease

When my dog Mac was diagnosed with Canine Cushing's disease, the vet prescribed Vetoryl, a medication he had to take twice a day. However, after starting the treatment, I noticed a concerning change—he lost his appetite in the morning, which was unusual for him, and his overall energy levels dropped dramatically. Worried about his health, I took him back to the vet, where they advised me to stop the medication. The very next day, he started feeling better, and after follow-up bloodwork, we discovered that his Cortisol levels remained stable even without the prescription drugs.

After doing some research, I learned that Cordyceps mushrooms support adrenal gland health and help regulate Cortisol levels naturally. I started giving him our 5-in-1 mushroom blend, and to my surprise, that's all he needed to maintain his health. He is thriving without the side effects of prescription medication, thanks to the natural power of medicinal mushrooms.

 

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